Here, we investigated the regenerative response of pancreatic islets following moderate beta-cell loss in mice using two diffenet models: one rapid beta-cell targeted synchronous cell death by using the RIPDTR model, and one slow heterogeneous cell death by using streptozotocin…
Together with our collaborators from the BETAUPREG Group (financed by NO Grants 2014– 2021, under Project contract no. 21/2020 (RO-NO-2019-0544), Andreas and Andrei mapped the molecular fingerprint of early insulitis in a cohort of NOD mice ranging from 4 to…
Wishing good luck for Fatemeh, Ann Charlotte and Natalie which will defend their work for the following Master Theses. Congratulations for really great work and presentations! Fatemeh Sadat Heidari Rahmatabadi Grade A Thesis Title: “Using SC-islet and murine models to…
We are very happy to annouce the publication of a study led by Dr. Hanne Scholz focusing on cell identity dynamics and insights into insulin secretagogues when employing stem cell-derived islets for disease modeling. Here, Chencheng focused on understanding the…
Friday, 21st of June 2024, Andreas will defend his work on the PhD thesis! The defense will take place at HUS – Glasblokkene, Auditorium Glasblokkene 1, for the meeting details please follow this link. Trial Lecture: Friday 21. June 2024…
Here, Andreas built and analysed several timelines along the first year of life of different mouse models to understand how pancreatic endocrine islets are maturing and then age. By combining transgenic systems, global transcriptomics, pathway analysis, cell biology and physiology,…
On May 30-31, the Scandinavian Physiological Society (SPS) Board met with the Editorial Team of Acta Physiologica in Berlin 🇩🇪 “The meeting provided an opportunity to see new and familiar faces and discuss various topics around Acta Physiologica. Special thanks…
We are honored and excited to participate and contribute to the new KG Jebsen Center for Myeloid Blood Cancer. The main goal is to develop diagnostics at the single-cell level that reveal response to treatment after hours and days, and…
The fourth Nordic meeting on Development, Stem Cells, and Regeneration will be organised jointly by the Michael Sars Centre at the University of Bergen, the Swedish Developmental Biology Organisation (SWEDBO), the Finnish Society for Developmental Biology (FSDB) and affiliated Norway /…
We are honored and excited to participate and contribute to the new KG Jebsen Center for Myeloid Blood Cancer. The main goal is to develop diagnostics at the single-cell level that reveal response to treatment after hours and days, and…
During pancreas development the HH-signaling modulations plays an essential role, its inactivation being absolutely required for pancreas organogenesis, even slight ectopic activation compromising this process. Moreover, the pathway also plays a role in adult pancreas regeneration, its inactivation promoting regenerative…
We are very happy to annouce the publication of a study led by Dr. Hanne Scholz focusing on the impact of glucose concentration in regulating the differentiation of induced pluripotent stem cells toward insulin-producing cells. We previously showed that chronically…