by Shayla Sharmine The endocrine pancreas produces hormones that regulate glucose homeostasis in the body. Among three major regulatory hormone-producing cell types, delta cell is known to regulate the secretion of somatostatin that counter-regulates insulin and glucagon production through intra-islet…
by Thomas Aga Legøy Today, Nature published a new feature examining the most cited papers of the twenty-first century (Pearson et al., 2025). The most cited paper is naturally connected to the neural-inspired algorithms that laid the foundation for deep…
We are very happy and grateful to learn that the Norwegian Research Council @forskningsradet will continue to support our research for the next 5 years! We are delighted to continue our work on HNF1A by adding a Time-Dimension of Islet…
by Kaykobad Hossain Bladder cancer (BC) is the tenth most common cancer type worldwide. Muscle-invasive bladder cancer (MIBC) is the more aggressive type that is defined by invasion of the detrusor layer of the bladder and concurrent metastasis to adjacent…
WNT-4 real? A proposed paracrine player in β-cell function and glycemic control by Ulrik Larsen Diabetes is a multifactorial disorder commonly characterized by the loss or dysfunction of pancreatic β-cell, which play a central role in insulin secretion. β-cells have…
by Fatemeh Rahmatabadi Acute myeloid leukemia (AML) is an aggressive blood cancer marked by the rapid expansion of immature myeloblasts. Despite progress in targeted therapies, resistance remains a major obstacle, especially in patients with mutations that impact the MAPK and…
C-MYC is organising a Single Cell Satellite Seminar one day prior to the CCBIO’s 13th Annual Symposium aiming to bring into discussion recent advancements in single-cell genomics, transcriptomics, proteomics, and preclinical trials. The subsidized registration fee for academic participants is…
Rethinking the Overshadowed by Shayla Sharmine Glucose homeostasis in the human body is maintained through a delicate balance between glucose production, uptake, and storage, primarily regulated by endocrine hormones secreted from the pancreas. While insulin from β cells and glucagon…
Congratulations to Kayko who received funding from the L. Meltzers Universitetsstiftelse for the proposal titled ”Deciphering the role of WNT4 in bladder cancer using patient-derived organoids”! Bladder cancer (BC) is the most common cancer of the urinary tract and currently…
by Thomas Aga Legøy Bisphenol S (BPS) is extensively utilized in various commercial and manufacturing products, including cleaning detergents, plating solvents, phenolic resins, and thermal paper. Previous studies have demonstrated that BPS is closely associated with acute cytotoxicity, neurotoxicity, immunotoxicity,…
Here, Kayko investigated the proteomic landscape changes along a timeline within the 12 days of treatment with a potent carcinogen, BBN (N-butyl-N-(4-hydroxybutyl) nitrosamine), to understand how oncogenic transformation occurs in mouse bladder. By combining transgenic models, TMT-plex proteomics, pathway analysis,…
