Georg Cato Seeberg will start working on his Master Thesis for one year in our lab (2024-2025) as part of Master in Biomedical Sciences organised by the Department of Biomedicine. Georg will work with Lucas under the supervision of Simona on the…
Welcome Agnes!
Agnes Sandvik will start working on her Master Thesis for one year in our lab (2024-2025) as part of Master’s in biology organised by the Department of Biological Sciences (BIO). Agnes will work with Lucas Unger under the supervision of Luiza…
Journal Club: Could Microplastics Protect Us Against Persistent Organic Pollutants?
by Thomas Aga Legøy In traditional toxicology, the focus has been on evaluating the adverse effects of individual chemicals and establishing safe exposure levels. However, there is a growing recognition that real-world exposures involve complex mixtures of chemicals, which may…
Journal Club: Morphometry and mechanical instability at the onset of epithelial bladder cancer
by Kaykobad Hossain Carcinomas are the most prevalent form of cancer, which is characterized by malignancies of epithelial tissues. Bladder cancer, one of the costliest cancers to treat, is ideal to investigate epithelial morphogenesis at early stages of tumorigenesis due…
Journal Club: Cold memories control whole-body thermoregulatory responses
Something positive about Norwegian winter? Cold memories control whole-body thermoregulatory responses by Ulrik Larsen Exposure to cold induces long-lasting changes in physiology that persist beyond the cold period itself. This study investigates the cellular and molecular mechanisms of this phenomenon,…
Journal Club: Snake venom protection by a cocktail of varespladib and broadly neutralizing human antibodies
by Lucas Unger This study explores the development of a potential universal antivenom by combining monoclonal antibodies with a small-molecule inhibitor. By isolating antibodies from a hyperimmune human donor with extensive venom exposure (Tim Friede, who injected himself over 800…
PrePrint: SAM: A FIJI-Based Tool for Semi-Automated Quantification of Cytoplasmic Expression in Cells
After many months of persuasion, Lucas published his semi-automated quantification tool that he developed over 3 years of quantification of thousands of sc-islets and pancreatic sections. His tool is now available both in GitHUB and as a manuscript (currently as…
Editorial: Targeting Inflammation in Type 2 Diabetes: The Emerging Role of Decorin
Shayla Sharmine and I had the opportunity to write an editorial about recent work published in Acta Physiologica on the role of Decorin on pancreatic islets. Shayla did a really great job on generating a nice figure summarising the published…
Journal Club: ERK1/2 and p38α/β Signaling in Tumor Cell Quiescence: Opportunities to Control Dormant Residual Disease
by Fatemeh Rahmatabadi This article by Sosa et al. explores the biology of disseminated tumor cells (DTCs), which are central to cancer relapses and metastasis. DTCs can spread early during tumor development—even from non-invasive lesions—and persist in distant organs such…
Journal Club: Real time somatostatin detection assay reveals somatostatin hypersecretion in T2D patient derived single islets
by Shayla Sharmine The endocrine pancreas produces hormones that regulate glucose homeostasis in the body. Among three major regulatory hormone-producing cell types, delta cell is known to regulate the secretion of somatostatin that counter-regulates insulin and glucagon production through intra-islet…
Journal Club: Impact does not mean world-changing
by Thomas Aga Legøy Today, Nature published a new feature examining the most cited papers of the twenty-first century (Pearson et al., 2025). The most cited paper is naturally connected to the neural-inspired algorithms that laid the foundation for deep…
Grant award: FRIPRO Researcher Project for Experienced Scientists
We are very happy and grateful to learn that the Norwegian Research Council @forskningsradet will continue to support our research for the next 5 years! We are delighted to continue our work on HNF1A by adding a Time-Dimension of Islet…