Our work on the impact of diet challenges on Hnf1a-deficient beta-cells is now published in Acta Physiologica! Congratulations Shayla, Thomas and Lucas!
by Fatemeh Rahmatabadi: This week’s journal club focuses on a study from Drugs in R&D (2024) aiming to assess the activity of trametinib against a panel of tumor cells from patients with AML
by Agnes Sandvik: This week’s journal club focuses on a study from Front. Bioeng. Biotechnol. (2023) aiming to assess the effects of a microencapsulation system based on the use of “human elastin-like recombinamers” on SC-islets
Welcome to the 61st Contact Meeting of the Norwegian Bioscience Society (formerly known as the Norwegian Biochemistry Society)! The NBS Contact Meeting is a great opportunity for researchers and students to present their work to a national audience. This year’s…
by Shayla Sharmine: This week’s journal club focuses on a study from non-coding RNA (2025) aiming to to investigate the roles of the mouse homolog of Hnf1aos1 in liver function, gene expression, and cellular processes.
by Kaykobad Hossain: in this article, researchers investigated an experimental reductive cell division process, termed mitomeiosis, wherein non-replicated (2n2c) somatic genomes are prematurely forced to divide following transplantation into the metaphase cytoplasm of enucleated human oocytes.
by Thomas: This week’s journal club focuses on a study from Nature Communications (2025) showing that local transplantation of iPSC-derived neural progenitor cells (NPCs) improves brain repair and long-term functional recovery in stroke-injured mice.
Simona will give a talk about new projects in the lab and work in progress at the next Nordic Developmental Biology Seminar (2nd of October 2025, 12:00).
by Ulrik: This week’s journal club focuses on a study from Nature (2025) showing that acute stress activates medial amygdala neurons that innervate the ventromedial hypothalamus, which precipitates hyperglycaemia and hypophagia.
by Lucas Unger This week’s journal club focuses on a study from Cell Metabolism (2025) describing a regulatory axis where HNF1A controls transcription of A1CF, which orchestrates an RNA splicing program encompassing genes that regulate β cell function.
by Shayla Sharmine This week’s journal club focuses on a study from Frontiers in Immunology (2025) aiming to assess the role of autophagy in b-cell health and survival, and whether defects in autophagy render islets more immunogenic.
by Camille Belliard: This week’s journal club discusses a landmark first-in-human study published in Cell (2024) investigating autologous transplantation of chemically induced pluripotent stem cell-derived islets (CiPSC-islets) for type 1 diabetes (T1D).
by Fatemeh Rahmatabadi Venetoclax resistance in acute lymphoblastic leukemia is characterized by increased mitochondrial activity and can be overcome by co-targeting oxidative phosphorylation. Enzenmüller et al. explore why B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells sometimes resist the BCL-2 inhibitor…