Research Paper: Endocrine Disrupting Chemical Exposure During Differentiation Alters the Proliferation-Maturation Balance in Stem-Cell islets

This study proposes hiPSCs derived SC-islet differentiation as model to study development impact of EDCs on human pancreatic endocrine cell development and maturation. Using a cocktail of BPA, BPS and trans-nonachlor provided comparable results with in vivo studies of fetus exposure to BPA. Congratulations June, Thomas and Lucas!

Collaboration PrePrint: MODY mutations in transcription factors HNF1A and HNF1B affect the production of interferon signaling proteins: evidence at the proteome level

Our collaboration with our neighbouring lab continues with Ksenia performing quantitative label-free mass spectrometry, by employing both data-dependent and data-independent acquisition methods, on our cell line model for HNF1A “hot-spot” mutation. Lucas performed in vitro differentiation until pancreatic progenitor stage…

World Diabetes Day at Glasblokkene

On the occasion of World Diabetes Day, we invite you to a lunch seminar. The seminar starts with lunch at 11:00 in the auditorium in Glasblokkene, Block 8, and will offer two exciting lectures from Simon Dankel and Thomas Aga Legøy that will shed light on current topics within diabetes research.