We are very happy and grateful to learn that the Norwegian Research Council @forskningsradet will continue to support our research for the next 5 years! We are delighted to continue our work on HNF1A by adding a Time-Dimension of Islet…
Something positive about Norwegian winter? Cold memories control whole-body thermoregulatory responses by Ulrik Larsen Exposure to cold induces long-lasting changes in physiology that persist beyond the cold period itself. This study investigates the cellular and molecular mechanisms of this phenomenon,…
by Lucas Unger This study explores the development of a potential universal antivenom by combining monoclonal antibodies with a small-molecule inhibitor. By isolating antibodies from a hyperimmune human donor with extensive venom exposure (Tim Friede, who injected himself over 800…
After many months of persuasion, Lucas published his semi-automated quantification tool that he developed over 3 years of quantification of thousands of sc-islets and pancreatic sections. His tool is now available both in GitHUB and as a manuscript (currently as…
Shayla Sharmine and I had the opportunity to write an editorial about recent work published in Acta Physiologica on the role of Decorin on pancreatic islets. Shayla did a really great job on generating a nice figure summarising the published…
by Fatemeh Rahmatabadi This article by Sosa et al. explores the biology of disseminated tumor cells (DTCs), which are central to cancer relapses and metastasis. DTCs can spread early during tumor development—even from non-invasive lesions—and persist in distant organs such…
by Shayla Sharmine The endocrine pancreas produces hormones that regulate glucose homeostasis in the body. Among three major regulatory hormone-producing cell types, delta cell is known to regulate the secretion of somatostatin that counter-regulates insulin and glucagon production through intra-islet…
by Thomas Aga Legøy Today, Nature published a new feature examining the most cited papers of the twenty-first century (Pearson et al., 2025). The most cited paper is naturally connected to the neural-inspired algorithms that laid the foundation for deep…
by Kaykobad Hossain Bladder cancer (BC) is the tenth most common cancer type worldwide. Muscle-invasive bladder cancer (MIBC) is the more aggressive type that is defined by invasion of the detrusor layer of the bladder and concurrent metastasis to adjacent…
WNT-4 real? A proposed paracrine player in β-cell function and glycemic control by Ulrik Larsen Diabetes is a multifactorial disorder commonly characterized by the loss or dysfunction of pancreatic β-cell, which play a central role in insulin secretion. β-cells have…
by Fatemeh Rahmatabadi Acute myeloid leukemia (AML) is an aggressive blood cancer marked by the rapid expansion of immature myeloblasts. Despite progress in targeted therapies, resistance remains a major obstacle, especially in patients with mutations that impact the MAPK and…
C-MYC is organising a Single Cell Satellite Seminar one day prior to the CCBIO’s 13th Annual Symposium aiming to bring into discussion recent advancements in single-cell genomics, transcriptomics, proteomics, and preclinical trials. The subsidized registration fee for academic participants is…
Rethinking the Overshadowed by Shayla Sharmine Glucose homeostasis in the human body is maintained through a delicate balance between glucose production, uptake, and storage, primarily regulated by endocrine hormones secreted from the pancreas. While insulin from β cells and glucagon…