Luiza will give a talk about new developments in the lab and work on bladders at the next CCBIO Seminar (11th of December 2025, 14:30).
Speaking at CCBIO Seminar: Luiza Ghila
Journal Club: Pharmacology and toxicology of the novel investigational agent Cantrixil
by Fatemeh Rahmatabadi: This week’s journal club focuses on a study from Cancer Chemother. Pharmacol. (2017) promoting Cantrixil as a promising anti-cancer agent targeting resilient cancer-stem–cell populations.
Research Paper: Endocrine Disrupting Chemical Exposure During Differentiation Alters the Proliferation-Maturation Balance in Stem-Cell islets
This study proposes hiPSCs derived SC-islet differentiation as model to study development impact of EDCs on human pancreatic endocrine cell development and maturation. Using a cocktail of BPA, BPS and trans-nonachlor provided comparable results with in vivo studies of fetus exposure to BPA. Congratulations June, Thomas and Lucas!
Collaboration PrePrint: MODY mutations in transcription factors HNF1A and HNF1B affect the production of interferon signaling proteins: evidence at the proteome level
Our collaboration with our neighbouring lab continues with Ksenia performing quantitative label-free mass spectrometry, by employing both data-dependent and data-independent acquisition methods, on our cell line model for HNF1A “hot-spot” mutation. Lucas performed in vitro differentiation until pancreatic progenitor stage…
World Diabetes Day at Glasblokkene
On the occasion of World Diabetes Day, we invite you to a lunch seminar. The seminar starts with lunch at 11:00 in the auditorium in Glasblokkene, Block 8, and will offer two exciting lectures from Simon Dankel and Thomas Aga Legøy that will shed light on current topics within diabetes research.
Journal Club: Repeated head trauma causes neuron loss and inflammation in young athletes
by Ulrik: This week’s journal club focuses on a study from Nature (2025) characterizing the early cellular changes that might lead to chronic traumatic encephalopathy in young athletes exposed to repetitive head impacts.
Research Paper: Caloric Restriction Substantially Improves Glucose Regulation in Mice With Hnf1a‐Deficient Beta‐Cells
Our work on the impact of diet challenges on Hnf1a-deficient beta-cells is now published in Acta Physiologica! Congratulations Shayla, Thomas and Lucas!
Journal Club: Trametinib Sensitivity is Defined by a Myeloid Differentiation Profile in Acute Myeloid Leukemia
by Fatemeh Rahmatabadi: This week’s journal club focuses on a study from Drugs in R&D (2024) aiming to assess the activity of trametinib against a panel of tumor cells from patients with AML
Journal Club: Human induced pluripotent stem cells (hiPSC), enveloped in elastin-like recombinamers for cell therapy of type 1 diabetes mellitus (T1D)
by Agnes Sandvik: This week’s journal club focuses on a study from Front. Bioeng. Biotechnol. (2023) aiming to assess the effects of a microencapsulation system based on the use of “human elastin-like recombinamers” on SC-islets
61st NBS Contact Meeting, January 21 – 24, 2026
Welcome to the 61st Contact Meeting of the Norwegian Bioscience Society (formerly known as the Norwegian Biochemistry Society)! The NBS Contact Meeting is a great opportunity for researchers and students to present their work to a national audience. This year’s…
Journal Club: Hepatic Lipid metabolism and Immune pathways are regulated in LncRNA Hnf1aos1-knockdown mice
by Shayla Sharmine: This week’s journal club focuses on a study from non-coding RNA (2025) aiming to to investigate the roles of the mouse homolog of Hnf1aos1 in liver function, gene expression, and cellular processes.
Journal Club: Induction of experimental cell division to generate cells with reduced chromosome ploidy
by Kaykobad Hossain: in this article, researchers investigated an experimental reductive cell division process, termed mitomeiosis, wherein non-replicated (2n2c) somatic genomes are prematurely forced to divide following transplantation into the metaphase cytoplasm of enucleated human oocytes.