Journal Club: Sex-specific differences in glucose metabolism and pancreatic function in streptozotocin-induced diabetic mice: The protective role of estrogen

Can Sex Difference shape glucose regulation? by Shayla Sharmine This week’s journal club focuses on a study from Biochemical and Biophysical Research Communications (2025) exploring the protective role of estrogen in glucose regulation.  To explore the impact of sex difference,…

Journal Club: CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction

by Lucas Unger Yang et al. demonstrate that HHEX is a lineage-restricting transcription factor essential for pancreas specification from foregut progenitors. Through CRISPR-Cas9 loss-of-function screening combined with hiPSC differentiation and single-cell multiomics, the study reveals that deletion of HHEX diverts…

Midway Evaluation: Ulrik

Wishing good luck to Ulrik having his midway evaluation today! Thesis Title: “Mouse-ing around with islet cells: unveiling the tissue repair puzzle” Examining committee Internal examiner 1: Prof. Bjørn Tore Gjertsen Internal examiner 2: Dr. Heidrun Vethe Supervisors Simona Chera,…

Welcome Camille!

camille

Camille Belliard, currently pursuing an engineering degree in biotechnology at ENSTBB (Bordeaux INP) started a 4-months summer internship in our lab (June-September 2025). She will work with Lucas and Agnes on reprogramming T1D patient fibroblasts into iPSC and their differentiation…