Tag: Thomas Legøy

Research Paper: Endocrine Disrupting Chemical Exposure During Differentiation Alters the Proliferation-Maturation Balance in Stem-Cell islets

This study proposes hiPSCs derived SC-islet differentiation as model to study development impact of EDCs on human pancreatic endocrine cell development and maturation. Using a cocktail of BPA, BPS and trans-nonachlor provided comparable results with in vivo studies of fetus exposure to BPA. Congratulations June, Thomas and Lucas!

Journal Club: Bisphenol S exposure promotes stemness of triple-negative breast cancer cells via regulating Gli1-mediated Sonic hedgehog pathway

by Thomas Aga Legøy Bisphenol S (BPS) is extensively utilized in various commercial and manufacturing products, including cleaning detergents, plating solvents, phenolic resins, and thermal paper. Previous studies have demonstrated that BPS is closely associated with acute cytotoxicity, neurotoxicity, immunotoxicity,…

Thomas Aga Legøy

ORCID: 0000-0001-7619-6220 Scopus: 57200084387 Google Scholar: Legøy Research Gate: Legøy SCIENTIFIC CAREER Since 2022 Postdoctoral Fellow at Center for Diabetes Research, Department of Clinical Science, Faculty of Medicine, University of Bergen, Norway 2021 – 2022 Researcher – Center for Diabetes…