It’s hard to believe that Thomas is leaving us! While we will miss your presence here, we know you will achieve great things in your new adventure.
Farewell to: Thomas Aga Legøy
Tag: Thomas Legøy
Research Paper: Endocrine Disrupting Chemical Exposure During Differentiation Alters the Proliferation-Maturation Balance in Stem-Cell islets
This study proposes hiPSCs derived SC-islet differentiation as model to study development impact of EDCs on human pancreatic endocrine cell development and maturation. Using a cocktail of BPA, BPS and trans-nonachlor provided comparable results with in vivo studies of fetus exposure to BPA. Congratulations June, Thomas and Lucas!
Journal Club: Neural xenografts contribute to long-term recovery in stroke via molecular graft-host crosstalk
by Thomas: This week’s journal club focuses on a study from Nature Communications (2025) showing that local transplantation of iPSC-derived neural progenitor cells (NPCs) improves brain repair and long-term functional recovery in stroke-injured mice.
Journal Club: Could Microplastics Protect Us Against Persistent Organic Pollutants?
by Thomas Aga Legøy In traditional toxicology, the focus has been on evaluating the adverse effects of individual chemicals and establishing safe exposure levels. However, there is a growing recognition that real-world exposures involve complex mixtures of chemicals, which may…
Journal Club: Impact does not mean world-changing
by Thomas Aga Legøy Today, Nature published a new feature examining the most cited papers of the twenty-first century (Pearson et al., 2025). The most cited paper is naturally connected to the neural-inspired algorithms that laid the foundation for deep…
Journal Club: Bisphenol S exposure promotes stemness of triple-negative breast cancer cells via regulating Gli1-mediated Sonic hedgehog pathway
by Thomas Aga Legøy Bisphenol S (BPS) is extensively utilized in various commercial and manufacturing products, including cleaning detergents, plating solvents, phenolic resins, and thermal paper. Previous studies have demonstrated that BPS is closely associated with acute cytotoxicity, neurotoxicity, immunotoxicity,…
Journal Club: Impact of Bisphenol A on Gut Microbiota Composition and Its Association with Obesity in Children
by Thomas Aga Legøy The gut microbiota has garnered significant attention in recent years due to its critical role in maintaining physiological health. A balanced gut microbiota is associated with overall well-being, whereas dysbiosis is linked to the development and…