A detailed study into alpha-cells transcriptional changes upon massive ablation of beta-cells carried out in collaboration with Dr. Santiago Rodríguez-Seguí and Prof. Pedro Herrera groups was published today, and we show that: α-cells undergo stage-specific transcriptional changes 5- and 15-days…
Tag: research
Book Chapter: A Method for Encapsulation and Transplantation into Diabetic Mice of hiPSC-Derived Pancreatic Progenitors
Pancreatic islet endocrine cells generated from patient-derived induced pluripotent stem cells represent a great strategy for both disease modeling and regenerative medicine. Nevertheless, these cells inherently miss the effects of the intricate network of systemic signals characterizing the living organisms.…