For the past five years, our collaborator Helge Ræder and us showed that human induced pluripotent stem cells (hiPSC) provide an excellent tool for disease modelling. However, in vitro differentiation is highly sensitive to culture conditions. By re-creating a spatial…
A detailed study into alpha-cells transcriptional changes upon massive ablation of beta-cells carried out in collaboration with Dr. Santiago Rodríguez-Seguí and Prof. Pedro Herrera groups was published today, and we show that: α-cells undergo stage-specific transcriptional changes 5- and 15-days…
Pancreatic islet endocrine cells generated from patient-derived induced pluripotent stem cells represent a great strategy for both disease modeling and regenerative medicine. Nevertheless, these cells inherently miss the effects of the intricate network of systemic signals characterizing the living organisms.…
Congratulations to Andreas Mathisen, our PhD student, for obtaining one year mobility fellowship from Faculty of Medicine, University of Bergen, to study and work at University of Geneva, Switzerland! We are proud of you!
I am very happy to announce that we got the cover of the December Issue: Thank you Miri for the immunofluorescence picture, yes – it looks like a mouse, doesn’t it!? Also, many thanks to Charna and Vlad for this…
I had recently the great pleasure to contribute to a collaboration study led by Dr. Charna Dibner (from the Division of Endocrinology, Diabetes, Hypertension and Nutrition, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva) deciphering the…
I am invited by the organizers to give a talk on Islet Cell-Fate Dynamic at UNIGE’s Diabetes Center Seminar Series. The seminar will take place on October 5th, 2020 at CMU, room B04.2222