Here, we designed a pilot study to comprehensively identify the diversity of global proteome signatures and the deviation from normal homeostasis in randomly selected human-isolated islet samples. By using Tandem Mass Tag 16-plex proteomics, we focused on the recurrently observed…
Another fruitful collaboration working on proteomics analyses with a team led by Magnus Berle. In this study, we compared two groups of patients with colon cancer with similar stage, stratified based on the presence or absence of recurrence. The main…
For the past five years, our collaborator Helge Ræder and us showed that human induced pluripotent stem cells (hiPSC) provide an excellent tool for disease modelling. However, in vitro differentiation is highly sensitive to culture conditions. By re-creating a spatial…
Our latest work on iPSC-derived human pancreatic progenitors differentiation is now out for Early View: The main goal of this study was to assess the effects of elevated glucose concentrations exposure during the last stages of guided in vitro differentiation…
Congratulation to Yngvild for her published article, in which our collaborators show that: some reprogrammed cell lines present an unstable state leading to spontaneously differentiate and change their cellular phenotype and colony morphology; by comparing the proteome landscapes of 20…