Our work on the impact of diet challenges on Hnf1a-deficient beta-cells is now published in Acta Physiologica! Congratulations Shayla, Thomas and Lucas!
by Shayla Sharmine: This week’s journal club focuses on a study from non-coding RNA (2025) aiming to to investigate the roles of the mouse homolog of Hnf1aos1 in liver function, gene expression, and cellular processes.
by Shayla Sharmine This week’s journal club focuses on a study from Frontiers in Immunology (2025) aiming to assess the role of autophagy in b-cell health and survival, and whether defects in autophagy render islets more immunogenic.
Can Sex Difference shape glucose regulation? by Shayla Sharmine This week’s journal club focuses on a study from Biochemical and Biophysical Research Communications (2025) exploring the protective role of estrogen in glucose regulation. To explore the impact of sex difference,…
Shayla Sharmine and I had the opportunity to write an editorial about recent work published in Acta Physiologica on the role of Decorin on pancreatic islets. Shayla did a really great job on generating a nice figure summarising the published…
by Shayla Sharmine The endocrine pancreas produces hormones that regulate glucose homeostasis in the body. Among three major regulatory hormone-producing cell types, delta cell is known to regulate the secretion of somatostatin that counter-regulates insulin and glucagon production through intra-islet…
Rethinking the Overshadowed by Shayla Sharmine Glucose homeostasis in the human body is maintained through a delicate balance between glucose production, uptake, and storage, primarily regulated by endocrine hormones secreted from the pancreas. While insulin from β cells and glucagon…