Pancreatic islet endocrine cells generated from patient-derived induced pluripotent stem cells represent a great strategy for both disease modeling and regenerative medicine. Nevertheless, these cells inherently miss the effects of the intricate network of systemic signals characterizing the living organisms.…
I had recently the great pleasure to contribute to a collaboration study led by Dr. Charna Dibner (from the Division of Endocrinology, Diabetes, Hypertension and Nutrition, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva) deciphering the…
Our recent study on iPSC-derived human pancreatic progenitors initial response to in vivo is now published: The main goal of this study was to demultiplex and characterize the initial response of the hiPSC-derived differentiating pancreatic progenitors to the in vivo…
Our study on iPSC-derived human pancreatic progenitors in vitro differentiation is now published: The main goal of this study was to characterize the impact of cell confinement on the pancreatic islet signature during the guided in vitro differentiation of alginate…
Our latest work on iPSC-derived human pancreatic progenitors differentiation is now out for Early View: The main goal of this study was to characterize global effect of brief and prolonged in vivo hyperglycaemia exposure on the cell fate acquisition and…
Our latest review on regeneration breaks in different animal models is now out for Early View. We discuss about: Most attention on tissue regeneration has focused on the exploration of positive cues promoting or allowing the engagement of natural cellular…
Congratulation to Yngvild for her published article, in which our collaborators show that: some reprogrammed cell lines present an unstable state leading to spontaneously differentiate and change their cellular phenotype and colony morphology; by comparing the proteome landscapes of 20…