by Kaykobad Hossain Bladder cancer (BC) is the tenth most common cancer type worldwide. Muscle-invasive bladder cancer (MIBC) is the more aggressive type that is defined by invasion of the detrusor layer of the bladder and concurrent metastasis to adjacent…
WNT-4 real? A proposed paracrine player in β-cell function and glycemic control by Ulrik Larsen Diabetes is a multifactorial disorder commonly characterized by the loss or dysfunction of pancreatic β-cell, which play a central role in insulin secretion. β-cells have…
by Fatemeh Rahmatabadi Acute myeloid leukemia (AML) is an aggressive blood cancer marked by the rapid expansion of immature myeloblasts. Despite progress in targeted therapies, resistance remains a major obstacle, especially in patients with mutations that impact the MAPK and…
Rethinking the Overshadowed by Shayla Sharmine Glucose homeostasis in the human body is maintained through a delicate balance between glucose production, uptake, and storage, primarily regulated by endocrine hormones secreted from the pancreas. While insulin from β cells and glucagon…
by Thomas Aga Legøy Bisphenol S (BPS) is extensively utilized in various commercial and manufacturing products, including cleaning detergents, plating solvents, phenolic resins, and thermal paper. Previous studies have demonstrated that BPS is closely associated with acute cytotoxicity, neurotoxicity, immunotoxicity,…
by Kaykobad Hossain Bladder cancer, like most cancers, is a heterogenous disease and the variability of the disease can be captured using molecular subtyping, which may result in more effective treatment options. Even though bladder cancer has been classified to…
by Ulrik Larsen Glucagon is traditionally seen as a pancreas-specific hormone, but evidence suggests an extra-pancreatic source that responds abnormally to oral glucose in diabetic patients. This study investigates whether the intestine could be responsible for this unexpected glucagon secretion. …