This week’s journal club focuses on a study from Cell Metabolism (2025) describing a regulatory axis where HNF1A controls transcription of A1CF, which orchestrates an RNA splicing program encompassing genes that regulate β cell function.
This week’s journal club focuses on a study from Frontiers in Immunology (2025) aiming to assess the role of autophagy in b-cell health and survival, and whether defects in autophagy render islets more immunogenic.
This week’s journal club discusses a landmark first-in-human study published in Cell (2024) investigating autologous transplantation of chemically induced pluripotent stem cell-derived islets (CiPSC-islets) for type 1 diabetes (T1D).
by Fatemeh Rahmatabadi Venetoclax resistance in acute lymphoblastic leukemia is characterized by increased mitochondrial activity and can be overcome by co-targeting oxidative phosphorylation. Enzenmüller et al. explore why B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells sometimes resist the BCL-2 inhibitor…
by Kaykobad Hossain: in this article, researchers applied adhesion measurements of cancer cells to predict metastatic ability in a mouse model.
Can Sex Difference shape glucose regulation? by Shayla Sharmine This week’s journal club focuses on a study from Biochemical and Biophysical Research Communications (2025) exploring the protective role of estrogen in glucose regulation. To explore the impact of sex difference,…
High fructose diet in early life is bad by Ulrik Larsen Inspired by a lab member constantly theorizing about HNF1A and the brain, I came across a study on how early-life high fructose exposure affects brain development, focusing on microglia…