by Shayla Sharmine: This week’s journal club focuses on a study from non-coding RNA (2025) aiming to to investigate the roles of the mouse homolog of Hnf1aos1 in liver function, gene expression, and cellular processes.
by Kaykobad Hossain: in this article, researchers investigated an experimental reductive cell division process, termed mitomeiosis, wherein non-replicated (2n2c) somatic genomes are prematurely forced to divide following transplantation into the metaphase cytoplasm of enucleated human oocytes.
by Thomas: This week’s journal club focuses on a study from Nature Communications (2025) showing that local transplantation of iPSC-derived neural progenitor cells (NPCs) improves brain repair and long-term functional recovery in stroke-injured mice.
by Ulrik: This week’s journal club focuses on a study from Nature (2025) showing that acute stress activates medial amygdala neurons that innervate the ventromedial hypothalamus, which precipitates hyperglycaemia and hypophagia.
by Lucas Unger This week’s journal club focuses on a study from Cell Metabolism (2025) describing a regulatory axis where HNF1A controls transcription of A1CF, which orchestrates an RNA splicing program encompassing genes that regulate β cell function.
by Camille Belliard: This week’s journal club discusses a landmark first-in-human study published in Cell (2024) investigating autologous transplantation of chemically induced pluripotent stem cell-derived islets (CiPSC-islets) for type 1 diabetes (T1D).
by Fatemeh Rahmatabadi Venetoclax resistance in acute lymphoblastic leukemia is characterized by increased mitochondrial activity and can be overcome by co-targeting oxidative phosphorylation. Enzenmüller et al. explore why B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells sometimes resist the BCL-2 inhibitor…