I am invited by the organizers to give a talk on Islet Cell-Fate Dynamic at UNIGE’s Diabetes Center Seminar Series. The seminar will take place on October 5th, 2020 at CMU, room B04.2222
Speaking at Diabetes Center Seminar (UNIGE) 2020
Tag: Simona Chera
Interview in our Department’s newsletter
If you want to read about my interview for “This week`s employee” in K2 News – our department newsletter please follow this link: https://k2info.w.uib.no/en/2020/09/03/ukens-ansatt-simona-chera/
Bergen Stem Cell Consortium Research Seminar
Simona and Luiza will present some work progress on different projects running in the lab at the Bergen Stem Cell Consortium Research Seminar on Friday, 12th of April 2019 at Glasblokkene
Collaboration Paper: glucose-sensing insulin-secreting human α-cells
Cell-identity switches, in which terminally differentiated cells are converted into different cell types when stressed, represent a widespread regenerative strategy in animals, yet they are poorly documented in mammals. In mice, some glucagon-producing pancreatic α-cells and somatostatin-producing δ-cells become insulin-expressing…
Research Paper: Specific protein signatures related to progression to muscular invasiveness in bladder cancer
Patients with bladder cancer need frequent controls over long follow-up time due to high recurrence rate and risk of conversion to muscle invasive cancer with poor prognosis. We identified cancer-related molecular signatures in apparently healthy bladder in patients with subsequent…
Collaboration Paper: Signals modulating identity changes of pancreatic α-cells
The mechanisms that restrict regeneration and maintain cell identity following injury are poorly characterized in higher vertebrates. Following β-cell loss, 1-2% of the glucagon-producing α-cells spontaneously engage in insulin production in mice. Here we explore the mechanisms inhibiting α-cell plasticity.…
Research Paper: β-cell proteomic landscape in differentiating MODY1 patient iPSC-derived cells
Current published protocols for targeted differentiation of human stem cells toward pancreatic β-cells fail to deliver sufficiently mature cells with functional properties comparable to human islet β-cells. We aimed to assess whether Wnt-modulation could promote the final protocol stages of…