Here, we investigated the regenerative response of pancreatic islets following moderate beta-cell loss in mice using two diffenet models: one rapid beta-cell targeted synchronous cell death by using the RIPDTR model, and one slow heterogeneous cell death by using streptozotocin…
We are very happy to annouce that our collaboration study led by Dr. Seung Kim (Professor in the Department of Developmental Biology at Stanford University), aiming at developing an immunocompetent B6 RIP-DTR mouse model permitting diabetes induction with 100% penetrance,…
I had recently the great pleasure to contribute to a study led by Dr. Seung Kim (Professor in the Department of Developmental Biology, at Stanford University School of Medicine) aiming for the development of B6 RIP-DTR mice, an immunocompetent line…
Pancreatic islet endocrine cells generated from patient-derived induced pluripotent stem cells represent a great strategy for both disease modeling and regenerative medicine. Nevertheless, these cells inherently miss the effects of the intricate network of systemic signals characterizing the living organisms.…