Many congratulations to Jakub and Marc on developing a new Python-based tool called ProHap that constructs protein sequence databases from phased genotypes of reference panels, and comes with pregenerated databases from field-reference haplotype panels. Thus ProHap empowers researchers to account…
Another collaborative study carried over during Simona’s sabbatical stay in Prof Charna Dibner research group at University of Geneva aiming at profiling the long-term modifications of lipid metabolism associated with massive weight loss following the Roux-en-Y gastric bypass surgery. Here, we…
We are very happy to annouce the publication of a study led by Dr. Hanne Scholz focusing on cell identity dynamics and insights into insulin secretagogues when employing stem cell-derived islets for disease modeling. Here, Chencheng focused on understanding the…
We are very happy to annouce the publication of a study led by Dr. Hanne Scholz focusing on the impact of glucose concentration in regulating the differentiation of induced pluripotent stem cells toward insulin-producing cells. We previously showed that chronically…
We are very happy to annouce the publication of a study led by Prof. Charna Dibner including work that Simona performed during her sabatical year at University of Geneva, during 2020-2021. In a multi-center study, daily regulation of lipid metabolism…
Induced pluripotent stem cells as a source for generating pancreatic islet endocrine cells represent a great research tool for deciphering the molecular mechanisms of lineage commitment, a layered multi-step process. Additionally, targeted gene silencing by using GapmeRs, short antisense oligonucleotides,…
We are very happy to annouce the publication of a study led by Dr. Ana Vacaru (Group Leader of the BetaUpreg Research Group, Institute of Cellular Biology and Pathology “Nicolae Simionescu”, Bucharest, Romania) investigating the link between bisphenol A (BPA)…