We are very happy and grateful to the Novo Nordic Foundation @novonordiskfond that will continue to support our research for the next 5 years! We are delighted to continue our work on the role of somatostatin-producing delta-cells in monogenic diabetes.…
Tag: MODY
Grant award: Diabetesforbundet forskningsfond
Grant award: FRIPRO Ground-breaking research Project
BETAUPREG: partners on a Ro-No Collaborative Research Project
FRIPRO Young Talent Research Project
STAMCELLER Young Talent Research Project
The Novo Nordisk Foundation Excellence Project grant
Diabetes mellitus is a group of metabolic diseases defined by high blood sugar values caused by the inability of the body to produce and/or use insulin. All forms of diabetes are ultimately characterized by a decrease in the number of functional insulin-producing cells (β-cells), hence a cure for insulin-dependent diabetes types will require their regeneration or replacement. Generally, the most efficient regenerative strategies are the ones involving cell self-renewal capacity. Nevertheless, in mammals, the β-cell proliferative capacity is very low after birth and decreases even further with age. The overall aim of this proposal is to elucidate and reverse the molecular age-switch controlling the gradual impairment of β-cell self-renewal potential by using two murine models of monogenic diabetes.