by Kaykobad Hossain: in this article, researchers investigated an experimental reductive cell division process, termed mitomeiosis, wherein non-replicated (2n2c) somatic genomes are prematurely forced to divide following transplantation into the metaphase cytoplasm of enucleated human oocytes.
by Kaykobad Hossain: in this article, researchers applied adhesion measurements of cancer cells to predict metastatic ability in a mouse model.
by Kaykobad Hossain Carcinomas are the most prevalent form of cancer, which is characterized by malignancies of epithelial tissues. Bladder cancer, one of the costliest cancers to treat, is ideal to investigate epithelial morphogenesis at early stages of tumorigenesis due…
by Kaykobad Hossain Bladder cancer (BC) is the tenth most common cancer type worldwide. Muscle-invasive bladder cancer (MIBC) is the more aggressive type that is defined by invasion of the detrusor layer of the bladder and concurrent metastasis to adjacent…
Congratulations to Kayko who received funding from the L. Meltzers Universitetsstiftelse for the proposal titled ”Deciphering the role of WNT4 in bladder cancer using patient-derived organoids”! Bladder cancer (BC) is the most common cancer of the urinary tract and currently…
Here, Kayko investigated the proteomic landscape changes along a timeline within the 12 days of treatment with a potent carcinogen, BBN (N-butyl-N-(4-hydroxybutyl) nitrosamine), to understand how oncogenic transformation occurs in mouse bladder. By combining transgenic models, TMT-plex proteomics, pathway analysis,…
by Kaykobad Hossain Bladder cancer, like most cancers, is a heterogenous disease and the variability of the disease can be captured using molecular subtyping, which may result in more effective treatment options. Even though bladder cancer has been classified to…