We are very happy to annouce the publication of a study led by Dr. Hanne Scholz focusing on the impact of glucose concentration in regulating the differentiation of induced pluripotent stem cells toward insulin-producing cells. We previously showed that chronically…
Tag: Human iPSC
Book Chapter: Targeted Gene Silencing by Using GapmeRs in Differentiating Human-Induced Pluripotent Stem Cells (hiPSC) Toward Pancreatic Progenitors
Induced pluripotent stem cells as a source for generating pancreatic islet endocrine cells represent a great research tool for deciphering the molecular mechanisms of lineage commitment, a layered multi-step process. Additionally, targeted gene silencing by using GapmeRs, short antisense oligonucleotides,…
Book Chapter: A Method for Encapsulation and Transplantation into Diabetic Mice of hiPSC-Derived Pancreatic Progenitors
Pancreatic islet endocrine cells generated from patient-derived induced pluripotent stem cells represent a great strategy for both disease modeling and regenerative medicine. Nevertheless, these cells inherently miss the effects of the intricate network of systemic signals characterizing the living organisms.…