by Fatemeh Rahmatabadi: This week’s journal club focuses on a study from Scientific Reports (2025) exploring the specific molecular mechanisms of Siglec6 CAR-T therapy in acute myeloid leukemia.
by Fatemeh Rahmatabadi: This week’s journal club focuses on a study from Blood (2017) on JAK1/2 and BCL2 inhibitors in AML
by Fatemeh Rahmatabadi: This week’s journal club focuses on a study from Scientific Reports (2020) investigating the ERK activity in immature leukemic cells involed in clonal selection in AML
by Fatemeh Rahmatabadi: This week’s journal club focuses on a study from Cancer Chemother. Pharmacol. (2017) promoting Cantrixil as a promising anti-cancer agent targeting resilient cancer-stem–cell populations.
by Fatemeh Rahmatabadi: This week’s journal club focuses on a study from Drugs in R&D (2024) aiming to assess the activity of trametinib against a panel of tumor cells from patients with AML
by Fatemeh Rahmatabadi Venetoclax resistance in acute lymphoblastic leukemia is characterized by increased mitochondrial activity and can be overcome by co-targeting oxidative phosphorylation. Enzenmüller et al. explore why B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells sometimes resist the BCL-2 inhibitor…
by Fatemeh Rahmatabadi This study by Hirosawa et al. investigates the effect of the p38 MAPK inhibitor SB202190 on acute myeloid leukemia (AML) cells. While p38 signaling is typically associated with stress responses and growth inhibition, treatment of AML cell…