Many congratulations to Jakub and Marc on developing a new Python-based tool called ProHap that constructs protein sequence databases from phased genotypes of reference panels, and comes with pregenerated databases from field-reference haplotype panels. Thus ProHap empowers researchers to account haplotypic diversity in proteomic searches.
Continue your reading here:
ProHap enables human proteomic database generation accounting for population diversity
Authors: Jakub Vašíček, Ksenia G. Kuznetsova, Dafni Skiadopoulou, Lucas Unger, Simona Chera, Luiza M. Ghila, Nuno Bandeira, Pål R. Njølstad, Stefan Johansson, Stefan Bruckner, Lukas Käll, Marc Vaudel
Nature Methods, December 9, 2024
DOI information:10.1038/s41592-024-02506-0