During pancreas development the HH-signaling modulations plays an essential role, its inactivation being absolutely required for pancreas organogenesis, even slight ectopic activation compromising this process. Moreover, the pathway also plays a role in adult pancreas regeneration, its inactivation promoting regenerative…
We are very happy to annouce the publication of a study led by Dr. Hanne Scholz focusing on the impact of glucose concentration in regulating the differentiation of induced pluripotent stem cells toward insulin-producing cells. We previously showed that chronically…
We are very happy to annouce the publication of a study led by Prof. Charna Dibner including work that Simona performed during her sabatical year at University of Geneva, during 2020-2021. In a multi-center study, daily regulation of lipid metabolism…
Here, we designed a pilot study to comprehensively identify the diversity of global proteome signatures and the deviation from normal homeostasis in randomly selected human-isolated islet samples. By using Tandem Mass Tag 16-plex proteomics, we focused on the recurrently observed…
Induced pluripotent stem cells as a source for generating pancreatic islet endocrine cells represent a great research tool for deciphering the molecular mechanisms of lineage commitment, a layered multi-step process. Additionally, targeted gene silencing by using GapmeRs, short antisense oligonucleotides,…
We are very happy to annouce the publication of a study led by Dr. Ana Vacaru (Group Leader of the BetaUpreg Research Group, Institute of Cellular Biology and Pathology “Nicolae Simionescu”, Bucharest, Romania) investigating the link between bisphenol A (BPA)…
We have the pleasure to co-edit a Joint Collection at Communication Biology and Scientific Reports on Patterning and Polarity in Morphogenesis The collection will be edited by 4 Editors: Simona Chera, Caroline Formstone, Vladimir Korzh & Edwina McGlinn This Collection welcomes…